| Resoluut | |
| Resume.io | |
| Resyca B.V. | |
| Retail Rocket | |
| RetailVista | Flevoland |
| RetSoft | |
| RetSoft B.V. | Groningen |
| Reudink Software | Drenthe |
| Reveall | |
| Revisely B.V. | |
| Revive Adserver | |
| Revo Capital | North Holland |
| RevSpace | |
| Reynen Court, Inc. | North Holland |
| RFID Platform Nederland | South Holland |
| RGB+ Automatisering | Overijssel |
| RheinBrücke IT Consulting B.V. | |
| Rian B.V. | North Brabant |
| RiboPro | |
| Ricoh Nederland B.V. | North Brabant |
| Rideau B.V. | |
| RIFF | North Holland |
| RightClick | North Holland |
| Rijksakademie | |
| Rijksdienst Caribisch Nederland | |
| Rijksinstituut voor Volksgezondheid en Milieu | |
| Rijksoverheid | |
| Rijkswaterstaat | |
| Rijs Solutions | |
| Rinkel B.V. | |
| RIPE NCC | North Holland |
| Riscure Security Lab | South Holland |
| RIset B.V. | North Holland |
| Rita Personal Data B.V. | |
| Ritense | North Holland |
| Rits Consultancy | |
| Rizemail | |
| RM Data | North Holland |
| RoadEO | |
| Roald Craenen | Limburg |
| Roam.ai | |
| Roamler B.V. | |
| Robert Peterson | |
| ROBES Informatica B.V. | Gelderland |
| Robin | Gelderland |
| Robin Mobile | |
| Robin Radar | South Holland |
| RoboHouse | |
| RoboMiri | South Holland |
| Robota Softwarehouse B.V. | North Holland |