| Cyfluencer | |
| Cyfox | |
| Cyhawk Ventures | Tel Aviv District |
| Cylus | Tel Aviv District |
| Cymulate | Central District |
| Cynergy | Tel Aviv District |
| Cynomi Ltd | Tel Aviv District |
| Cypago | Tel Aviv District |
| Cyrus Venture Partners | Tel Aviv District |
| Cytactic | |
| CytoReason Ltd | Tel Aviv District |
| D-Fend Solutions AD Ltd | Central District |
| D-Webs | Tel Aviv District |
| D.H.Media Company | Tel Aviv District |
| D.M.O. | Tel Aviv District |
| Dagesh | Tel Aviv District |
| Daily.dev | Central District |
| Daina Reed Web Design | Tel Aviv District |
| Daronet Technologies | Tel Aviv District |
| Databank | Central District |
| Databin | Southern District |
| DataCenter.co.il | Central District |
| DataCube | Central District |
| DataHarbor | Central District |
| Datalead AI | |
| Dataloop Ltd | Tel Aviv District |
| Datamind | Tel Aviv District |
| Datumate | Northern District |
| David Yellin Academic College of Education | |
| DBBbalance.com | Tel Aviv District |
| DBS-H | Jerusalem District |
| DealHub Ltd | Jerusalem District |
| Decell Technologies Ltd | |
| Deceptive Bytes | Tel Aviv District |
| Deci | Tel Aviv District |
| DeePathology.ai | Central District |
| Degel Software | Jerusalem District |
| Deliverider | Tel Aviv District |
| Delta Ventures | Central District |
| Depoint | Southern District |
| Design-Studio | Tel Aviv District |
| detectIT | Tel Aviv District |
| Devalore Ltd | Central District |
| Developers.Institute | Tel Aviv District |
| DevGeekWeek Conference | |
| DeviceTotal | |
| Devlion | Haifa District |
| DevOcean | Tel Aviv District |
| Dexcel Ltd | Haifa District |
| DFiant Ltd | |