| Équipements Sunterra, Inc. | Quebec |
| Equispheres | |
| EquiTech Communications | Ontario |
| Equity Business Services, Inc. | British Columbia |
| Equustek Solutions, Inc. | British Columbia |
| EQWin Software, Inc. | British Columbia |
| Eralis Software, Inc. | Saskatchewan |
| Erden | Quebec |
| ERE - Information Security Auditors | Ontario |
| Ergo Vancouver | British Columbia |
| ErgoCanada.com | Saskatchewan |
| Ergon Technologies | Quebec |
| Ergoweb Canada, Inc. | Quebec |
| Éric Paquet Spécialiste Googel AdWords | Quebec |
| Ericsson in Canada | |
| EricTechnicien.com | Quebec |
| Ernest Barbaric | Alberta |
| Erod Communications | Quebec |
| ERP Buddies, Inc. | |
| ERP Connex, Inc. | Quebec |
| ERP Consulting | |
| ERPMastering, Inc. | Ontario |
| ERPs360.inc | |
| Erso Informatique, Inc. | Quebec |
| ESAC | Ontario |
| eSalesTraffic | Ontario |
| eSAX | |
| eScanData | British Columbia |
| Escape Computer Center | Ontario |
| eSchedule, Inc. | Ontario |
| eScribe Software Ltd | |
| eSentire, Inc. | Ontario |
| ESET Canada, Inc. | Ontario |
| ESG Média, Inc. | Quebec |
| ESGTree | Ontario |
| ESI Technologies | Quebec |
| eSight Corporation | Ontario |
| ESimplified, Inc. | Ontario |
| esitecreations.ca | Ontario |
| Eskalad | Quebec |
| eSolution | |
| eSolutions ameublement | |
| eSonar | |
| Esourceparts.ca | |
| Espace CDPQ | Quebec |
| Espace Courbe | Quebec |
| Espace d'accélération et de croissance de l'Abitibi-Témiscamingue | |
| Espace Entrepreneuriat Région Thetford | Quebec |
| Espace québécois de concertation sur les pratiques d'approvisionnement responsable | Quebec |
| Espace Régional d'Accélération et de Croissance de la Gaspésie | |