| Southern Computer Services | |
| Southern Cross Consulting Ltd | Hampshire |
| Southern IT Ltd | |
| Southern IT Networks Ltd | East Sussex |
| Southern Logic Ltd | Dorset |
| Southern Regional College | |
| Southfield Systems Ltd | North Yorkshire |
| Southwark College | |
| Southwell Computer Center | Nottinghamshire |
| Southwest Data Networks Ltd | Devon |
| Souveren | |
| Sova Assessment Ltd | |
| Soven Developer | |
| Sovereign Business Integration Group plc | Greater London |
| Sovereigncctv | Merseyside |
| soVision Ltd | Bristol |
| SovTech UK | |
| SP Electronics Ltd | Lancashire |
| Spa Computers | Warwickshire |
| Spa Technology Ltd | Gloucestershire |
| Space & Time Media Ltd | |
| Space City | |
| Space Crew | |
| Space DOTS | |
| Space Forge Ltd | |
| Space Forge Ltd | |
| Space Forms Ltd | |
| Space Galleon Ltd | |
| Space I.D. Ltd | |
| Space Made Group Ltd | |
| Space on White | |
| Space Solutions (Scotland) Ltd | |
| Space Tech Expo | |
| Space Ventures Investors | |
| Space Zero Ltd | |
| Space-Careers | |
| SPACE4 | |
| Space48 | |
| Spacebit | |
| Spacecake | |
| SpaceCareers.uk | |
| Spaced Digital Ltd | |
| Spaceflow | |
| SpaceForm | |
| SpacePath Communications | |
| SpacePay | |
| SpaceScotland | |
| SpaceTech Analysis | |
| Spacetech International | |
| SpaceTechEuro Ltd | |