| Softline UK | |
| Softlink Solutions Ltd | Essex |
| Softlok | Lancashire |
| Softomate Solutions Ltd | |
| Softoo Ltd | |
| Softools | |
| Softrader Ltd | |
| SoftSoft Ltd | Bedfordshire |
| Softstart UK Ltd | Norfolk |
| Softwair UK Ltd | Lincolnshire |
| Software 4 Dentists | Lincolnshire |
| Software Acumen Ltd | Cardiff |
| Software Development UK | |
| Software Dynamics Ltd | Swansea |
| Software Matters | Dorset |
| Software of Excellence | Kent |
| Software Outsourcing Services | |
| Software Scotland Ltd | |
| Software Solutions Consultancy Ltd | |
| Software Solved Ltd | |
| Software Systems | Aberdeen |
| Software Systems Europe Ltd | Greater Manchester |
| Software Testing News | |
| Software Verify Ltd | Suffolk |
| SoftwareMajor | |
| SoftwarePromotions Ltd | Dorset |
| Softwire | |
| SOHO IT Solutions | |
| Soho Square Capital Group | |
| SoHo66 | Tyne and Wear |
| SOKO Media | |
| Sol-Tec Ltd | Berkshire |
| Solar Computer Systems Ltd | Northamptonshire |
| Solar Digital | |
| Solar Inks Ltd | |
| Solar PV Technology Ltd | |
| Solaris Offgrid | |
| SolasCure Ltd | |
| Solbeg Ltd | |
| Solcom Ltd | Isle of Wight |
| Soldo Software Ltd | |
| Sole Media | |
| Solent University | Hampshire |
| Solicitors Own Software Ltd | Somerset |
| Solid Designs Internet Solutions Ltd | Derbyshire |
| Solid Solutions Management Ltd | |
| Solidgate | |
| Solifi | Buckinghamshire |
| Solirius Ltd | |
| Sollatek | Berkshire |