| Ehter Solutions | Buckinghamshire |
| Eigentek Ltd | Hampshire |
| Eight Roads | |
| eightsquared | Essex |
| Eighty3 Creative Ltd | |
| EIMS Ltd | Dorset |
| Eintech Ltd | |
| EIS | Kent |
| Eitex | West Yorkshire |
| Eka VC | |
| Eke Security Ltd | Gloucestershire |
| EKF Diagnostics | |
| Ekm Systems Ltd | Lancashire |
| El Capitan Digital Ltd | |
| El Roboto | |
| ELAA Technology | |
| Elan Networks Ltd | Glasgow |
| ElanCRM | Essex |
| Elasmogen | |
| Elasmogen Ltd | |
| Eldentech Ltd | |
| ELE | Greater London |
| Eleco Software Ltd | |
| Elecosoft | Buckinghamshire |
| Electric Media Ltd | |
| Electric Putty | East Sussex |
| Electric Studio | Oxfordshire |
| Electrify Video Partners | |
| Electrocom Networks Ltd | |
| Electrokinetic | |
| Electron Electronics | Surrey |
| Electronic Business Systems Ltd | West Midlands |
| Electronic Centre | Belfast |
| Electronic Power Systems Ltd | |
| Electronic Reading Systems Ltd | Bedfordshire |
| Electronic Technicians Ltd | Dorset |
| Electropages Ltd | Dorset |
| Electropages Media Ltd | |
| Electrowise Computers | Devon |
| Elegant Digital Ltd | |
| Elegant IT | Northamptonshire |
| Element | |
| Element 78 Solutions Ltd | Bristol |
| Element Materials Technology | |
| Element Seven Digital Ltd | |
| Element UK | |
| Elemental Software | |
| Elementary Digital | |
| Elementary Digital Ltd | |
| Elements Technology | |