| One Marketing | |
| Onexo | |
| Optimen | |
| Orange Studio | Mexico City |
| Orbit Media One | Chihuahua |
| Orcius | Puebla |
| Orda Web | |
| Orion Startups | Mexico City |
| OT Consulting | Nuevo León |
| OverCode Solutions | |
| Overflow Labs | |
| Pacto POS | Mexico City |
| Pagaloop | Mexico City |
| Páginas web en Mérida | Mexico City |
| Paginas Web Profesionales | Mexico City |
| Pago Por Clic México | Mexico City |
| Palenca | |
| Palmas | Nuevo León |
| Panngea | Mexico City |
| Papalotl Technologies | |
| Papaya Design | |
| Parrot Software | |
| Parvada Cowork | Nuevo León |
| Pastor International Marketing, S.A. de C.V. | Quintana Roo |
| Pauta Creativa | Mexico City |
| Payment Power México, S.A. de C.V. | |
| PC Capital | Mexico City |
| PC COM | Mexico City |
| PC Enlaces | San Luis Potosí |
| PC Office | Mexico City |
| Pc Rent | Mexico City |
| PC.com.mx | Mexico City |
| Pcdigital.com.mx | Veracruz |
| PCDomino.com | Tamaulipas |
| PCEL | Mexico City |
| Pcounter México | Mexico City |
| Pcredcom | Nuevo León |
| PCWorld México | Mexico City |
| Pepper Technologies México | Mexico City |
| Perfect Choice | Jalisco |
| Persto | Mexico City |
| Pice-Software | Jalisco |
| Piensoweb | |
| Pisicionart | Querétaro |
| Pix2Byte | Puebla |
| Pixan | Jalisco |
| Pixela | Mexico City |
| Pixelmedia | Mexico City |
| Pixzelle Studio | |
| PlanDigital | |