| MDO Tecnología | Jalisco |
| MECA Agency | |
| Mediatrain S.A. de C.V. | Mexico City |
| Medisist | Jalisco |
| Medix | Mexico City |
| Mega Plaza | Mexico City |
| Mega.com, S.A. de C.V. | Mexico City |
| Megacomputer S.A. de C.V. | Jalisco |
| Megatron | Mexico City |
| Mendel | Mexico City |
| Mendoza Nava y Asociados del Golfo, S.A. de C.V. | Puebla |
| Merca-Tech | Mexico City |
| Merca3w | Mexico City |
| Mercancun | Quintana Roo |
| MercSoft | Mexico City |
| Merkaimagen | Mexico City |
| Mertakus 360 | |
| Meta Consultores | Mexico City |
| Metodika | |
| Metta Coworking | Jalisco |
| Mex.tl | Guanajuato |
| Mexagon, S.A. De C.V. | Mexico City |
| Mexbalia | Mexico City |
| Mexcompany | Mexico City |
| Mexhosting | Mexico City |
| México High Security | Mexico City |
| MexicoSEO | |
| Mexis | Mexico City |
| Mexline | Hidalgo |
| MexPiaginas | |
| Mexternet, S.A. de C.V. | Mexico City |
| MexWebs | Jalisco |
| Mi Empresa Online Diseño Web y Tiendas Online | |
| MiCiudad.com | Jalisco |
| Microbit | Mexico City |
| Microsoft México | Mexico City |
| Microsys | Nuevo León |
| MIDM Diseño y Multimedia S. de R.L. de C.V. | State of Mexico |
| Migesa | Mexico City |
| Migonetworks | Mexico City |
| Millenium Networks | Mexico City |
| Minu | |
| Minu Servicios, S.A.P.I de C.V. | Mexico City |
| Miranda Partners | |
| Mitaro | Mexico City |
| MKTi | |
| MobileLab360 | |
| Mobilender, Inc. | Mexico City |
| Mobileware | Mexico City |
| ModuloWeb | Querétaro |