| Xaguar Soluciones | Mexico City |
| Xailna Internet Business Consulting | Mexico City |
| Xal Digital, S.A. de C.V. | State of Mexico |
| XAMAI | Mexico City |
| Xataka México | Mexico City |
| XB Ventures | Mexico City |
| Xerox Mexicana | Mexico City |
| XID | |
| Xideral | |
| Ximple | |
| Xipe Ltd | Sonora |
| Xnet Epsilon Soft | Chihuahua |
| Xochi Ventures, S.A.P.I. de C.V. | Mexico City |
| Xoles | Nuevo León |
| Xplaye | Nuevo León |
| XPS, S.A. de C.V. | Quintana Roo |
| Xstudio.mx | |
| XTI Systems | Mexico City |
| Ya Ganaste | Mexico City |
| Yana App, S.A.P.I. de C.V. | |
| Yana App, S.A.P.I. de C.V. | |
| Yave Smart Lending SPV, S.A.P.I. de C.V. | |
| YAY! Estudio de Diseño | Jalisco |
| Yaydoo | |
| Yealab | Chihuahua |
| Yoco | Yucatán |
| yotepresto | |
| Yubox, S.A.P.I. de C.V. | |
| Yuhu Marketplace, S.A. de C.V. | |
| Zafirosoft | Nuevo León |
| ZDApps | Mexico City |
| Zell, S.A. de C.V. | |
| Zellship | |
| Zeus Conultores | Mexico City |
| Zipvisual | Jalisco |
| Zona Personal | Mexico City |
| ZOOM Marketing Digital | |
| Zoombers | Mexico City |
| Zoomplanet | Mexico City |
| Zubale | Mexico City |
| Zubia People & Business | Mexico City |
| Zulu Ventures Capital | Jalisco |
| Zuma Tecnologías de Información | |