| Smily & BookingSync S.A.S. | |
| SMK | Paris |
| Smooth Code | |
| SMS Gold | Charente |
| smsmode | Bouches-du-Rhône |
| SMVI Informatique | Essonne |
| Snapp' | |
| SNEES | Sarthe |
| Snow Globe | |
| So App | |
| So Digital | Hauts-de-Seine |
| SOC Informatique | Bas-Rhin |
| Social Transport Solutions | |
| SocialCompare S.A.R.L. | Var |
| Socialyse Paris | |
| Sociel | Loire |
| Société ADCI | Marne |
| Société Française de Bioinformatique | |
| Société informatique de France | Essonne |
| Société Téléphonie Bordelaise Duplantier | Lot-et-Garonne |
| Socimet | Côte-d'Or |
| Socloz | |
| Socomore | |
| Socram Branque | |
| SodeaSoft | Pas-de-Calais |
| Sodern S.A. | |
| SoFAB | Alpes-Maritimes |
| SOFALI | |
| Sofft Industrie | Métropole de Lyon |
| Sofft Technologies | Métropole de Lyon |
| Sofialys | Seine-Maritime |
| Sofracs | Paris |
| Sofrecom | Val-de-Marne |
| Soft Concept | Métropole de Lyon |
| Soft-Lan Informatique | Indre |
| Softbuilder | |
| Softeam | Paris |
| Softeam Agency | Paris |
| SoftFluent | |
| Softing | Yvelines |
| Softinnov | |
| Softlaw S.A.S. | Paris |
| Softouest | Loire-Atlantique |
| Softthinks S.A.S. | |
| Softvallée | |
| Software Attitude | Seine-et-Marne |
| Software Domain | Loire-Atlantique |
| Software Heritage | |
| Softway Medical | |
| Sogelink | Métropole de Lyon |