| Sistec | Haute-Garonne |
| Sistel S.A.S. | Métropole de Lyon |
| Sistema Strategy | |
| Sisteo | Indre-et-Loire |
| Sit'Project | Vaucluse |
| Sitaci S.A.S. | Loire-Atlantique |
| Site Analyzer | |
| Site web Créations | Loire-Atlantique |
| Site-web.pro | Aveyron |
| SiteBoX | Gironde |
| SITEC- Société Informatique et Technologique Corse | Haute-Corse |
| Siteflow | |
| Siteparc | Paris |
| Sitepenalise.fr | |
| Sitescom | Oise |
| SiteW | |
| Siteweb65 | Hautes-Pyrénées |
| SiteWebPro | Métropole de Lyon |
| Sitodi | Bouches-du-Rhône |
| Sitowie | |
| SITSI | Hauts-de-Seine |
| Situaction | Nord |
| Sitweb concept | Bouches-du-Rhône |
| Siveco Group S.A. | Yvelines |
| SiVIEW | |
| SiWeb | Bouches-du-Rhône |
| SIWI | Paris |
| Six Design | Gironde |
| Six-Axe | Yvelines |
| Skaleet | |
| Skama | |
| Skapánê | |
| Skeepers | |
| Skello | Val-de-Marne |
| SKEMA Business School | |
| Sketchfab | Paris |
| Skill Software | Hauts-de-Seine |
| Skilld S.A.S. | |
| Skills | |
| Skilmi | |
| SKOD | |
| Skopeo | |
| SkyePharma | |
| Skynopy | |
| Skytech S.A.S. | |
| Slagon | Paris |
| Slapdigital | Paris |
| Slash Consulting | |
| SLIB | Paris |
| SLICE | Nord |