| Special Learning, Inc. | |
| Special Ops Security | California |
| Special Projects Group, Inc. | Massachusetts |
| Specialized Business Software | Ohio |
| Specialized Data Recovery | California |
| Specialized Data Systems | Connecticut |
| Specialized Electronics, Inc. | Texas |
| Specialized Resources, Inc. | Texas |
| Specialized Security Services | |
| Specialized Test Engineering, Inc. | Colorado |
| Specialty Cable Corporation | Connecticut |
| Specialty Product Technologies | North Carolina |
| Specialty Systems, Inc. | New Jersey |
| SpecialtySoft | North Carolina |
| SpeciCare | Georgia |
| Specifica, Inc. | |
| Speck Design | |
| Speck Media, Inc. | |
| Speclipse, Inc. | California |
| Speco Technologies | New York |
| SpecSoft.DEV, LLC | Wyoming |
| Specsources | Georgia |
| Spectel Research Corporation | California |
| Specter AI, LLC | |
| Specter Ops, Inc. | Virginia |
| Spective | |
| Spector | Massachusetts |
| Spectora | Colorado |
| Spectra East Communications | New York |
| Spectra Equipment Corporation | California |
| Spectra Logic Corporation | Colorado |
| Spectra Studio | |
| Spectra Systems Corporation | Rhode Island |
| Spectra Test Equipment, Inc. | California |
| Spectraforce Technologies | North Carolina |
| SpectraGenetics, Inc. | Pennsylvania |
| Spectral | New York |
| Spectral AI, Inc. | Texas |
| Spectral Instruments Imaging | |
| Spectral Systems, LLC | New York |
| Spectralink Corporation | Colorado |
| Spectrant | California |
| Spectrasonics.net | California |
| SpectraWAVE, Inc. | Massachusetts |
| Spectrio | Florida |
| Spectro Cloud | |
| Spectrocell, Inc. | |
| SpectroFilm, Inc. | Massachusetts |
| Spectrolab, Inc. | |
| Spectron Components, Inc. | California |