| St. Stephen Chamber of Commerce | |
| St. Stephen's University | New Brunswick |
| St. Thomas More College | |
| St. Thomas University | New Brunswick |
| Stable.work | |
| Stablecorp, Inc. | |
| Staccato AI, Inc. | |
| Stack Harbor | Quebec |
| STACK IT Recruitment | |
| StackAdapt, Inc. | Ontario |
| StackApps | |
| Stackera | |
| Stacktics | |
| Stackup | |
| Stactt Technical Solutions, Inc. | Ontario |
| Stadium Digital | Ontario |
| Stadium Live Studios, Inc. | |
| Staff Scheduler Pro | Manitoba |
| Staff Virtuel | |
| StaffScheduleCare | |
| StaffStat | |
| Staffvision Services, Inc. | Quebec |
| StageZero Life Sciences Ltd | |
| Stagsi | |
| Stambol | |
| StaminaSys | Quebec |
| Stand Out Online | British Columbia |
| Standard IP Telecom | Ontario |
| Standard Marketing Ltd | British Columbia |
| Standard Media Services, Inc. | Ontario |
| Standard Resume | |
| StandardFusion | |
| Standish Communications | Quebec |
| StandUp Ventures | |
| Stanford Design Ltd | Ontario |
| Staples Canada | Ontario |
| Star App Solutions | |
| STAR Computer Services | Ontario |
| Star Dot Hosting | Ontario |
| Star Global Advanced IT Corporation Ltd | British Columbia |
| Star Solutions International, Inc. | British Columbia |
| Star Telecom | Ontario |
| Stardust Computers & Services | British Columbia |
| StarElectronics.ca | British Columbia |
| StarFish Product Engineering, Inc. | |
| Starfish Systems | British Columbia |
| StarGarden | British Columbia |
| Stargate Connections, Inc. | British Columbia |
| StarkTMS | |
| StarLynx Remote Communications, Inc. | British Columbia |