| Prime Technologies | |
| PrimeCharts | KwaZulu-Natal |
| PrimeLogic | |
| Pro Web Design | |
| ProConSol IT Group | Limpopo |
| Prodesign (Pty) Ltd | Gauteng |
| Profida | Western Cape |
| Progressive Distributing Enterprises CC | Gauteng |
| Project 5 Website Design | Western Cape |
| Project Group | Western Cape |
| Prokon | Gauteng |
| Promatix | |
| Prop Data | KwaZulu-Natal |
| Propella Dev Team | Eastern Cape |
| PROpulsion | |
| ProSolutions | Gauteng |
| ProSysTech | Gauteng |
| Protium | |
| PSI Systems | Gauteng |
| PST Training | Western Cape |
| Psybergate | |
| Public Investment Corporation | |
| Pulacache | |
| Pure Web Solutions (Pty) Ltd | |
| Purple Turtle Group | |
| PyCon ZA | Gauteng |
| Python System Design | Gauteng |
| Q-Kon | Gauteng |
| QBinc | Western Cape |
| QNET Networking Solutions | |
| QoT Solutions | |
| Qrent | Gauteng |
| Qualica Technologies | Gauteng |
| Quantec Research | Gauteng |
| Quicksearch Hosting Company | KwaZulu-Natal |
| QuickSolve Advertising and IT Solutions | Free State |
| QuickSolve Website Design & Advertising Solutions | |
| Quickspace | Gauteng |
| QuikeFix.com IT Service | |
| Quintica | Gauteng |
| QWERTY Educational Design | Gauteng |
| R Media | KwaZulu-Natal |
| R-Technologies | Gauteng |
| RA Computer Systems | Eastern Cape |
| Rabtron | Gauteng |
| Rae & Associates | Gauteng |
| RainFin (Pty) Ltd | |
| Ramp Group | Western Cape |
| RapidBid South Africa | Gauteng |
| Rapidsoft | Gauteng |