| REO Elektronik AG | Zurich |
| ReportGPT | |
| ReproNovo | |
| Rescale | |
| ReSe Applications GmbH | St. Gallen |
| Resilio | |
| Resolve S.A. | |
| responsAbility Investments AG | |
| retailsolutions Schweiz AG | Zug |
| Retel Neuhausen AG | Schaffhausen |
| RetinAI Medical AG | |
| Revizto S.A. | |
| RGR Software AG | Zurich |
| Rheon Medical S.A. | |
| RhyGaze AG | |
| RhyGaze AG | |
| RhySearch | |
| Riedo Networks Ltd | |
| RightMesh AG | |
| RigiTech | |
| Ringier AG | |
| RISC-V International | |
| Riskart (Switzerland) SA | Ticino |
| RistanCASE | Zurich |
| Ritech Solutions AG | |
| Ritz & Häfliger Visuelle Kommunikation | Basel-Stadt |
| Rivero AG | |
| Rivia | |
| Rivopharm S.A. | |
| RIVR | |
| RIZ AG | Zurich |
| ROB Technologies AG | |
| RobOlympics.ch | St. Gallen |
| Robotec Solutions AG | Aargau |
| Rocket-Capital | |
| Rocketvax AG | |
| ROCKON Digital Evolution AG | |
| Roland Ringgenberg Technologies GmbH | |
| ROMAN - Consulting & Engineering AG | Zurich |
| Rontis | |
| RoomPriceGenie AG | |
| ROSE Technologies AG | |
| Rotronic AG | Zurich |
| Rovenso S.A. | |
| Roventa-Henex S.A. | |
| RTLabs Europe | |
| RTP GmbH | Zurich |
| RUAG Group | |
| Ruby Monstas Zürich | |
| Ruf Informatik AG | Zurich |