| e-trackit | Merseyside |
| E2 Media | Devon |
| E2E Solutions Ltd | West Midlands |
| E2E Studios Ltd | |
| E2E Technologies | |
| E2e-assure | |
| E3 Technical | |
| e9 | |
| e92plus | Greater London |
| EACS Ltd | Cambridgeshire |
| Eagle Genomics | |
| Eagle Intermedia | West Yorkshire |
| Eagle Web Solutions | Worcestershire |
| Earlham Institute | Norfolk |
| Earnr | |
| Earth Blox | |
| Earth-i Ltd | |
| Earthbanc | |
| EarthID | |
| Earthware | Hertfordshire |
| Easibuild | Ards and North Down |
| Easiserv | Northamptonshire |
| East Coast College | |
| East Devon IT Ltd | Devon |
| Easton College | |
| Eastside Co | West Midlands |
| Easy Convey Ltd | Surrey |
| Easy Data Recovery | Belfast |
| Easy Domains | |
| Easy Internet Services Ltd | Leicestershire |
| Easy PC | Kent |
| Easy Recovery | Belfast |
| Easy Software Ltd | |
| Easy Web Sites Ltd | |
| EasyBuild (Construction Software) Ltd | Hertfordshire |
| EasyByte Software Ltd | East Lothian |
| Easycopiers | Buckinghamshire |
| Easykey Ltd | Essex |
| easylifeIT | Cambridgeshire |
| easyNetworks | |
| EasyPC Ltd | |
| Easysoft Ltd | West Yorkshire |
| Easyspace Ltd | Glasgow |
| Easytech Solutions Ltd | Merseyside |
| Eau Rouge Rouge Ltd | |
| Eazipay Ltd | Cambridgeshire |
| Eazyweb | Cardiff |
| Eazyweb Internet Services Ltd | Cardiff |
| EB IT Support Ltd | |
| EBar Initiatives Ltd | |