| MainBrain | North Holland |
| Maintain Design | |
| Mair Therapeutics B.V. | |
| Makso Assemblage B.V. | Utrecht |
| Mambu B.V. | |
| Mamometric | |
| Mangelot Hosting | Overijssel |
| Manna Automatisering | North Holland |
| Mansystems | Gelderland |
| Manualmaster | South Holland |
| Manus Software Europe B.V. | South Holland |
| Mapcode | North Holland |
| MapGage | South Holland |
| MAPIQ | South Holland |
| Marco van Hylckama Vlieg | North Holland |
| Marcompaan | Gelderland |
| Margriet de Boer | |
| Marketing Databases International | North Holland |
| Marktlink Capital | |
| MarkUp | Gelderland |
| Marnix Academie | Utrecht |
| Marsman IT-Solutions | |
| Martin Fitzpatrick | Utrecht |
| Martinic | North Holland |
| Marvia | North Holland |
| Massive Splash | |
| Master IT | North Brabant |
| Masugro | Utrecht |
| Matas Electronics B.V. | North Brabant |
| MathGrapher | South Holland |
| Matisse Pharmaceuticals B.V. | |
| Matrixian B.V. | |
| Matsiemaal | |
| Maven Infotech | |
| Mavim B.V. | South Holland |
| Maxcode | |
| Maxcom B.V. | Gelderland |
| Maxlead | South Holland |
| Maxxton B.V. | Zeeland |
| MaXXus Communications | South Holland |
| Mazarine Energy | |
| MB Secure | |
| MCA Industrial Communication | |
| MCH information & communication | Utrecht |
| MCM Vaccine B.V. | |
| MCX Administration Services B.V. | Gelderland |
| MCXess B.V. | |
| MDA Consultancy | North Holland |
| MDF | |
| Meant2B ICT Professionals | Utrecht |