| Delta-N B.V. | South Holland |
| DeltaPi | |
| Deltares | South Holland |
| Deludi B.V. | North Holland |
| Demcon Hemics B.V. | |
| Den of Data | Utrecht |
| Denit Hosting Solutions | North Holland |
| Denko | Overijssel |
| DeNoize | South Holland |
| DENS | |
| Dept Holding B.V. | North Holland |
| Deputy IT B.V. | North Holland |
| DESelect B.V. | |
| Design Solutions | Gelderland |
| DesignBro | |
| DesignConsult | North Brabant |
| DesignThinkers Academy | North Holland |
| Desk Content Marketing | North Brabant |
| DeskProto | Utrecht |
| DESQ B.V. | Flevoland |
| Detail Technologies B.V. | |
| DetaSoft | Flevoland |
| Detron | Utrecht |
| Detron ICT Rental Solutions B.V. | Utrecht |
| Developers House | South Holland |
| Developers.nl | |
| DevelopGuidance | Flevoland |
| DEVENTit B.V. | Utrecht |
| Devise Analytics B.V. | |
| DevRepublic | Overijssel |
| Dewi Online | North Brabant |
| DEX Data Explorers | |
| Dexter | |
| DFF Ventures | |
| DG Graphic Design | North Holland |
| DGB Group N.V. | |
| DGMR Software B.V. | South Holland |
| DHost B.V. | North Holland |
| DHS Microtron B.V. | North Brabant |
| Di-Dis.com | North Brabant |
| Diabolo ICT B.V. | Gelderland |
| Diagnose.me B.V. | |
| Dialog | Utrecht |
| Diana Fea B.V. | South Holland |
| Didata Automatisering B.V. | Gelderland |
| Diepcreative | |
| Digi Assets | |
| Digi.Bio B.V. | |
| Digibytez | Friesland |
| DigiCal | |