| DLA ICT | Gelderland |
| DLN Solutions Company | |
| DNSlytics | |
| DO-IT Automatisering | Gelderland |
| DOC Opleiding & Training | |
| Dockview Industry Communications | |
| Docs-consult | |
| DocsVue Document Services | Gelderland |
| DOESUM | |
| Doktar | |
| Dolphin Publications | North Brabant |
| Dolphiq B.V. | Utrecht |
| Domeineiland.nl | Utrecht |
| Domeinstad | North Brabant |
| dominion.nl | South Holland |
| Donia Media | South Holland |
| Donkey Mobile | South Holland |
| DoodleSoft | |
| Doors Internet Marketing | Limburg |
| Dot Tk | North Holland |
| Dotcomschool | Flevoland |
| Dotsimpel | Drenthe |
| dotsolutions | Drenthe |
| Dott | North Holland |
| Dotweb Systems B.V. | North Holland |
| DoubleSmart | South Holland |
| DPDK B.V. | |
| DPI | South Holland |
| DPW B.V. | |
| Dragon Media Group | Utrecht |
| DRB-IT Solutions | |
| DreamHost.nl | South Holland |
| Dreamsolution | South Holland |
| Dreamwebs | Limburg |
| Drie-O Automatisering B.V. | North Brabant |
| Driebit | North Holland |
| DRIVIn | |
| DRM ICT Solutions | North Holland |
| DSG WEB | |
| DSH Electronics | South Holland |
| Dsignonline | Groningen |
| DTA Systems | South Holland |
| DTT | |
| Dualler | North Brabant |
| DuchCoders | |
| Duck for Cover | Utrecht |
| DuckDB | |
| Dudok Consulting | Utrecht |
| Dumaco Holding B.V. | |
| Dustin Netherlands B.V. | |