| Bugatone | Tel Aviv District |
| Bugsec Ltd | Central District |
| Buildots | Tel Aviv District |
| BuiltUp Ventures | Tel Aviv District |
| Buy4less | Tel Aviv District |
| Buzzer | Tel Aviv District |
| Bynet Business | Tel Aviv District |
| Bynet Data Communications | |
| Bytech Communications | Central District |
| C Mer Industries Ltd | Tel Aviv District |
| C2A-SEC Ltd | |
| Calanit Carmon | Central District |
| CallUp Net Ltd | Central District |
| Cámara Multilateral de Comercio y Cooperación Israel-Iberoamérica | |
| Camtek | |
| Camtek Ltd | Northern District |
| Can-Fite BioPharma Ltd | Central District |
| Candivore Ltd | Tel Aviv District |
| Cappsool Technologies Ltd | Tel Aviv District |
| CAPS Medical | Central District |
| Carambola Ltd | Central District |
| Carmel Cables | Tel Aviv District |
| Carmelon Digital Marketing | Tel Aviv District |
| Carmelon Digital Marketing | |
| Carpe Diem Solutions Ltd | Tel Aviv District |
| Carrar | |
| Carteav | Central District |
| CartiHeal Ltd | Central District |
| Caspit Ltd | Tel Aviv District |
| Catalyst Investments L.P. | Tel Aviv District |
| Catom | Haifa District |
| CAV Systems Ltd | Haifa District |
| CDI Systems Ltd | Jerusalem District |
| Cecilia.ai | Central District |
| Cedar (Israel) Financial Advisors Ltd | Tel Aviv District |
| CELARE | Central District |
| Celeno Communications | Central District |
| Cellbris Telecom | Central District |
| Cellcom | Central District |
| CelleBrite | Central District |
| CELLect Mobile Entertainment Ltd | Haifa District |
| Cellomat | Central District |
| Cellrox Ltd | |
| Center for Educational Technology | Tel Aviv District |
| Centraleyes Tech Ltd | Tel Aviv District |
| Ception Technologies | Jerusalem District |
| Cerca Partners | Central District |
| Cervello Ltd | Tel Aviv District |
| CGS Tower Networks | Central District |
| Chain Reaction Ltd | Northern District |