| Q1 Scientific | |
| QAD Precision | Dublin City Council |
| QMS Software Ltd | Dún Laoghaire-Rathdown County Council |
| Qualcom | Dublin City Council |
| Qualio | |
| Quality and Qualifications Ireland | |
| Quantmatix Ltd | |
| Quest Computing Ltd | Dublin City Council |
| Quest Systems | |
| RadioactivePages.com | Dublin City Council |
| Radiomation | Roscommon County Council |
| RadiusTechnologies | Waterford City and County Council |
| Rage4 Networks Ltd | Dublin City Council |
| Rainbow Communications | Dublin City Council |
| Rainmaker Business Technologies | |
| RankRocket | |
| Real World Analytics | |
| Realise4 | |
| RealSim | |
| realTime | Dún Laoghaire-Rathdown County Council |
| Realtime Technologies Ltd | Dublin City Council |
| Réaltra Space Systems Engineering | |
| Reconcile Engineering Ltd | Dublin City Council |
| RED C Research & Marketing Ltd | |
| Red Flag | Dublin City Council |
| Red Hot Web Design | |
| Red Lemonade Creative Co. | |
| Redbrick | Dublin City Council |
| RedFly Ltd | Dublin City Council |
| Redline Studios | |
| Redstorm | |
| Reflective Measurement Systems Ltd | |
| Register.ie | Dublin City Council |
| Register365.com | Dublin City Council |
| Relate Software | South Dublin County Council |
| Relevium Medical | |
| Remedy Bio | |
| Renaissance Contingency Services Ltd | Dún Laoghaire-Rathdown County Council |
| RenditionDigital International Ltd | |
| Renexxion Ireland Ltd | |
| RepairTech | South Dublin County Council |
| Reptile Haus | Dublin City Council |
| ResourceKraft | |
| Retail Solutions | Galway County Council |
| Return2Sender | |
| Revolution Software Development Ltd | |
| Ridge Consulting | Dún Laoghaire-Rathdown County Council |
| Right-Click | Dublin City Council |
| Riordan SEO Ltd | |
| RiskSystem | |