| PlotBox | |
| Plus 10 Coworking & Start-up Space | |
| Plus Promotions | |
| Pocket Anatomy | Galway City Council |
| Point Blank Digital Ltd | |
| Polypico Technologies Ltd | |
| POMS Cloud Ltd | |
| Poppulo | Cork City Council |
| Portobello Institute | |
| Portview Marketing Ltd | |
| Post Studio | |
| POStech Ltd | Dublin City Council |
| Power Capital | |
| PrideDesign | Cork City Council |
| Primary Position | Cork City Council |
| Prime Carrier | Dublin City Council |
| Principal Logistics Technologies | Dublin City Council |
| Priothera Ltd | |
| Priviti Management Services Ltd | |
| Pro SEO Ireland | |
| Process | Dublin City Council |
| Process 3D | |
| ProcurementExpress.com | |
| Prodata | |
| Professional Development | |
| Professional Training Solutions Ltd | Dublin City Council |
| Progressive College | |
| Project Central | |
| Project Objects Ltd | Meath County Council |
| PRONAV Clinical | |
| Proposition One (Ireland) Ltd | |
| Proseo.ie | |
| ProStrategy | Dublin City Council |
| Protectimus Ltd | |
| Protego Technologies Ltd | Meath County Council |
| Protex AI | |
| Prothena Corporation plc | |
| ProVascTec | |
| Proventus Digital | |
| ProVerum Ltd | |
| Provideam Ltd | Dublin City Council |
| Provizio Ltd | |
| PSRA Ltd | Wicklow County Council |
| Pubble | |
| Púca Technologies Ltd | Dublin City Council |
| Pulseway | |
| Pure Telecom | Dublin City Council |
| PurpleDecks Ltd | |
| Pyramid Consulting Ltd | Dublin City Council |
| Python Ireland | Dublin City Council |