| Proppos | Barcelona |
| Prored Comunicaciones, S.L. | Valencia |
| ProstComputer | Madrid |
| Prosur | |
| ProtectFive, S.L. | |
| ProvidersWeb | Madrid |
| Proxima Systems | Valladolid |
| ProyectoIP Intelligence Solutions, S.L. | Murcia |
| ProyectoresOK.com | Barcelona |
| Psinnova | Madrid |
| Psquared | Barcelona |
| Pulmobiotics, S.L. | Barcelona |
| Pulpo | Madrid |
| Pulson Informática, S.L.U. | Valencia |
| Pululart, S.L. | A Coruña |
| Purple Blob | |
| Pushinrec Estudio Multimedia | Barcelona |
| Putput Comunicacions, S.L. | Barcelona |
| PyCon ES | Granada |
| PyP Informatica | Granada |
| Q-Impact Investment Management, S.G.E.I.C., S.A. | |
| QA Solutions | Barcelona |
| QBXNet Ltd | Barcelona |
| QDQ Media, S.A.U. | Asturias |
| QEV Technologies | Barcelona |
| Qilimanjaro Quantum Tech | |
| QODE | Barcelona |
| Qontinuum Plus, S.L. | Barcelona |
| QSOFT | Lleida |
| Quaderno | Las Palmas |
| Quadralia, S.L. | Pontevedra |
| Quadram | Madrid |
| Qualidades, Especialistas en Nuevas Tecnologías, S.L. | Valencia |
| Qualix DoT | |
| Quantum Computation and Information Group at Universidad Complutense de Madrid | Madrid |
| Quark Inside, S.L. | Valladolid |
| Quaternium | |
| Que Happy Agencia Creativa | Madrid |
| Quelinka | |
| Quenohariayoporti | |
| Quental Technologies, S.L. | Madrid |
| Querry, S.A. | Málaga |
| Quibim, S.L. | Valencia |
| Quid Pro Quo Alquier Seguro Socimi, S.A. | Madrid |
| Quimera Software Company | Sevilla |
| Quinti | Lugo |
| Quipu | Barcelona |
| Quiter Servicios Informáticos, S.L. | Cantabria |
| Qurv | |
| Quside | Barcelona |