| Megacom | |
| Megamation Systems, Inc. | Ontario |
| MEGAMIGS | Quebec |
| Megastar Électroniques, Inc. | Quebec |
| MegaSys Enterprises Ltd | Alberta |
| Mégatech A.Q., Inc. | |
| Megatech Integrated Services Ltd | Ontario |
| Megawatsoft | Ontario |
| Megram Consulting Services Ltd | Ontario |
| Meizon Solutions | |
| Melamoon | |
| Melcher Media & Design | Saskatchewan |
| Melcher Studios | |
| Meliark | |
| Melissa Merriam Marketing | |
| Mellowood Medical, Inc. | |
| Melodic Creative | Ontario |
| Melsoft | Quebec |
| MelSoft Innovations, Inc. | Quebec |
| Member365 | |
| Membio | |
| Memco Controls | |
| Meme Media, Inc. | British Columbia |
| MementoDB, Inc. | |
| Memex Automation, Inc. | Ontario |
| Memofix Hitech Services, Inc. | Ontario |
| Memoland | Quebec |
| memontoPix | |
| Memorial University | Newfoundland and Labrador |
| Memorial University - Department of Computer Science | Newfoundland and Labrador |
| Memorial University - Department of Mathematics and Statistics | Newfoundland and Labrador |
| Memorial University - Electrical and Computer Engineering | Newfoundland and Labrador |
| Memorial University - Faculty of Business Administration | Newfoundland and Labrador |
| Memorial University Centre for Entrepreneurship | Newfoundland and Labrador |
| Memorial University of Newfoundland - Research Centres - Electrical and Computer Engineering | Newfoundland and Labrador |
| Memorial University of Newfoundland - The Launch | Newfoundland and Labrador |
| Memorial University Research Innovation Office | Newfoundland and Labrador |
| Memory Express, Inc. | Alberta |
| Memory Lane Computers | Alberta |
| MemoryDepot.com | Quebec |
| Memotec | Quebec |
| Memri Tech, Inc. | |
| Mems Vision | |
| Memtronik Innovations, Inc. | Quebec |
| Men With Pens | Quebec |
| Mendon Associates, Inc. | Ontario |
| Mentor Works | |
| MentorcliQ | |
| Menucool | British Columbia |
| MEP Technologies, Inc. | |