| Manoverboard, Inc. | Manitoba |
| ManTek Services | Manitoba |
| Mantella Venture Partners | Ontario |
| Manteo | |
| Mantic Software Canada | |
| Mantle Blockchain | |
| Mantle Technology | |
| Mantra Digital, Inc. | |
| Mantra Pharma, Inc. | |
| Mantralogix, Inc. | Ontario |
| Mantrax Software Solutions | |
| Manufactures Automation, Inc. | Ontario |
| Manufacturiers & Exportateurs du Québec | |
| Manufacturing Systems Research, Inc. | Ontario |
| Many Hats | |
| ManyCam ULC | |
| Map Design | Quebec |
| Mapgears, Inc. | Quebec |
| MaPlateforme Web, Inc. | Quebec |
| Maple | |
| Maple Advanced Robotics, Inc. | |
| Maple Clicks | |
| Maple Invest | |
| Maple Leaf Angels 48 | Ontario |
| Maple Leaf Communications | Ontario |
| Maple Moon Web Design, Inc. | Ontario |
| Maple Oak Computer Solutions, Inc. | British Columbia |
| Maplesoft | Ontario |
| Maplesoft Group | Ontario |
| Maplewave | Nova Scotia |
| Mapleweb | British Columbia |
| Maplr | |
| Mappedin | |
| MapYourProperty | |
| Mar-Kov | Ontario |
| Mar-Kov Computer Systems | Ontario |
| Mara Consulting | |
| Mara Renewables | |
| Marc Desfossés, Inc. | |
| Marc-André Lavoie | Quebec |
| Marcatix Technologies | Quebec |
| March Consulting Associates, Inc. | Saskatchewan |
| March Networks | Ontario |
| Marchsoft | Ontario |
| Marchtek | Ontario |
| Marchvale Technologies Ltd | Ontario |
| Marcourt Communications, Inc. | Ontario |
| Marecomms, Inc. | Nova Scotia |
| Margill | Quebec |
| Marigale | |