| Make Digital | |
| Make IT Solutions | Alberta |
| MakeCloudWork, Inc. | |
| MakeFashion | |
| MakerKids | |
| MakerMax | British Columbia |
| MakeShyft R.D.A. | Ontario |
| Maket | |
| MakeUseOf | Quebec |
| Makila Ai | |
| Making Things Work | Ontario |
| Making8 | Alberta |
| Maknet Corporation | Ontario |
| Mako Financial Technologies, Inc. | |
| MAL Manufacturing Automation Laboratories, Inc. | British Columbia |
| Malco Electrique, Inc. | |
| Malicius Consultation | Quebec |
| Malopan Communications, Inc. | Quebec |
| Maman AI | |
| Maman Biomedical, Inc. | |
| Management-Ware Solutions | Quebec |
| ManaVoid | Quebec |
| Manco Control Systems, Inc. | Manitoba |
| Mandala Systems | Nova Scotia |
| Manel, Inc. | |
| Manganese X Energy Corporation | |
| Mango IT | |
| Mango Media | |
| Mango Software, Inc. | |
| MangoCoders | |
| Mangrove | |
| Maniac Tools | British Columbia |
| Maniasoft | Quebec |
| Manic Media | Ontario |
| Manifold Data Mining, Inc. | Ontario |
| Manitoba Education Research and Learning Information Networks | Manitoba |
| Manitoba Hydro | |
| Manitoba Institute of Trades and Technology | Manitoba |
| Manitoba Research Network | Manitoba |
| Manitoba Robot Games | Manitoba |
| Manitoba Software Services | |
| Manitoba Technology Accelerator | Manitoba |
| Manitoba UNIX User Group | Manitoba |
| Manitou | |
| Mankua Software | British Columbia |
| Mann Group | Ontario |
| Mannarino Systems & Software, Inc. | Quebec |
| Manne Professional Consulting | Ontario |
| Mannin Research, Inc. | |
| Manning Search Marketing | Newfoundland and Labrador |