| MacGameStore, Inc. | Alberta |
| Macgasm | Ontario |
| Mach85, Inc. | |
| Mach9 Servers | Nova Scotia |
| Machine | Ontario |
| Machine Learning and the Market for Intelligence | Ontario |
| Machinery Analytics | |
| MacHOLL IT Services | |
| Machool Technologies Ltd | |
| Macinhome | British Columbia |
| Macintosh User Group of Ottawa | Ontario |
| MacKinnon, Bennett & Company, Inc. | |
| MacMechanic.ca | Alberta |
| MacMedics | Ontario |
| Macmout, Inc. | Ontario |
| Maconception | Quebec |
| Macpherson Publishing | Ontario |
| MacPixels.com | Quebec |
| MacQuébec | Quebec |
| MacRAE'S | Ontario |
| Macreo | Ontario |
| Macroblu | Ontario |
| Macropus Global | |
| Mactracker | Ontario |
| MacTweek | Ontario |
| Mad App Technologies | |
| Mad Hatter Technology, Inc. | Ontario |
| MAD-Web.ca | Ontario |
| Madison Avenue Advertising Agency | |
| Madison Solutions Web | |
| Madrigal Info Groupe Conseil, Inc. | Quebec |
| Madrigal Soft Tools | British Columbia |
| Mady Graphic Design | British Columbia |
| Maerix, Inc. | Quebec |
| Maestro | Ontario |
| Maestro Technologies | Quebec |
| MAG Intégration, Inc. | |
| Magazine MCI | Quebec |
| Magellan Aerospace | |
| MageMontreal.com | Quebec |
| Magen Group | Ontario |
| Magenta Web Design | |
| Magentrix Corporation | Ontario |
| Magex Technologies | Quebec |
| Magi Studios, Inc. | British Columbia |
| Magic Information Systems, Inc. | Ontario |
| MagickML | |
| MagicLamp Software | Nova Scotia |
| Magiclogic Optimization, Inc. | British Columbia |
| Magicplan | Quebec |