| Eastlink | Nova Scotia |
| Eastwind Design Studios | New Brunswick |
| EastwoodDesign | Nova Scotia |
| Easy Email Solutions | Ontario |
| Easy Ocean Technology Ltd | Nova Scotia |
| Easy on Net | |
| Easy Projects | Ontario |
| Easycloud | Quebec |
| EasyDeal | Quebec |
| easyDNS | Ontario |
| easyhome Ltd | Ontario |
| EasyHosting | New Brunswick |
| Easyleads | |
| Easypay Software Company | Ontario |
| EasyPEI Software, Inc. | Ontario |
| EasyPro Solutions | Ontario |
| EasySafety | |
| easyTechCare | Ontario |
| Eatata, Inc. | |
| Eaton College | |
| Eazify System | |
| EB Computers | British Columbia |
| EB Informatique, Inc. | |
| EB Media | Ontario |
| eBase Works | Ontario |
| EBGames Canada | Ontario |
| Ebizmedia | Ontario |
| eBool | |
| Ebovir Biotechnologie, Inc. | |
| EBOX, Inc. | Quebec |
| eBridge Connections | Ontario |
| Ebridge Marketing Solutions, Inc. | British Columbia |
| eBRP Solutions Network, Inc. | |
| EBS Canada, Inc. | Ontario |
| EBT Medical, Inc. | Ontario |
| eBuild.ca | Ontario |
| Ebunch | British Columbia |
| eBytes Computers, Inc. | Manitoba |
| EC Managed IT | British Columbia |
| EC Net Solutions | |
| EC Solutions | Quebec |
| ECA Technologies, Inc. | Ontario |
| eCampus Ontario | |
| Ecatalogs | Quebec |
| Eccentric Business Intelligence | |
| Ecentric Media, Inc. | British Columbia |
| Ecere Corporation | |
| Échange Internet de Montréal, Inc. | Quebec |
| Echo Byte Technologies | |
| Echo I.T. | British Columbia |