| CAS Web Design Studios | Gauteng |
| Cash Connect Management Solutions (Pty) Ltd | |
| Casson Media (Pty) Ltd | Gauteng |
| Causal Nexus | Gauteng |
| CBR Marketing | |
| CCI Technology Solutions | Western Cape |
| CCS Africa | Gauteng |
| CEIT Development CC | Gauteng |
| Cellfind | Gauteng |
| Cellphone Contracts | Gauteng |
| Central University of Technology | Free State |
| CEOS Technologies | Gauteng |
| Cerebus Server | Western Cape |
| Cerrex Consulting | Gauteng |
| Channel Mobile | Western Cape |
| CharlieMarkComputers | Gauteng |
| CharterQuest Institute | |
| ChaseWaterford (Pty) Ltd | Western Cape |
| Chillies | |
| Chillnet IT | Gauteng |
| CHM Vuwani Computer Solutions (Pty) Ltd | Gauteng |
| Christopher Yiangou Consulting | Western Cape |
| Chrome Software | KwaZulu-Natal |
| Cibecs | Gauteng |
| Cicom Technologies | Gauteng |
| Cinnabar Graphic Design | Western Cape |
| CipherWave | Gauteng |
| Circuit City Electronics | Gauteng |
| Cirrus TechVue | Gauteng |
| CIT Business Solutions | Gauteng |
| CityVarsity (Pty) Ltd | |
| Civic Group | Gauteng |
| Civil Designer | Western Cape |
| CJA Telecommunications | Gauteng |
| Clearline Protection Systems (Pty) Ltd | Gauteng |
| Click Africa Digital | Western Cape |
| Click This Solutions | Gauteng |
| Click-IT | Gauteng |
| Click2Sure | |
| Click4Ink | Gauteng |
| Clickalytic | |
| ClickMe | |
| ClickOn Technologies (Pty) Ltd | Gauteng |
| Clickshape (Pty) Ltd | Western Cape |
| Clockwork Acorn (Pty) Ltd | |
| Cloud Group | Gauteng |
| Cloud Services (Pty) Ltd | Gauteng |
| Cloudfusion | |
| CloudSmiths | |
| Cloudwise | |