| Sys-Guru | Gauteng |
| Systech Computing | Eastern Cape |
| System 5 | Gauteng |
| Systemic Logic | |
| SystemicLogic | Gauteng |
| SyteDigital | |
| Syzygy SEO | Gauteng |
| T-Grafix Graphic & Web Design | |
| T-Host-T | Gauteng |
| Tactile Technologies | Western Cape |
| Takealot.com | Western Cape |
| Taletso TVET College | |
| TalkWithUs Group | Western Cape |
| Tandem Create | |
| Tarsus On Demand | |
| Tarsus Technology Group | Gauteng |
| Tashari (Pty) Ltd | Gauteng |
| Teacup Technology | Western Cape |
| Team IT | Western Cape |
| Tech in Africa | Gauteng |
| Tech Personnel | Free State |
| TechCentral | Gauteng |
| TechFinancials | Gauteng |
| techinfo.co.za | Eastern Cape |
| Technews Publishing (Pty) Ltd | Gauteng |
| TechniSolve Software CC | Gauteng |
| Techno World Components | KwaZulu-Natal |
| TechnoDezi (Pty) Ltd | Gauteng |
| Technology Innovation Agency | Gauteng |
| Technopark Stellenbosch | Western Cape |
| Technoview Diverse Training Solutions | KwaZulu-Natal |
| TechSmart.co.za | Gauteng |
| TECHSPO Cape Town | |
| TECHSPO Johannesburg | |
| Techsys Digital | Western Cape |
| TechTribe Accelerator | Gauteng |
| Tecleo Data Recovery and Digital Forensics Lab | Gauteng |
| Teebos Computers | Northern Cape |
| Telebar | Gauteng |
| Telemedia | Gauteng |
| Telkom SA SOC Ltd | Gauteng |
| Tellumat (Pty) Ltd | Western Cape |
| Telspace | Gauteng |
| Telspace Africa | Gauteng |
| Telviva | Western Cape |
| Tenfifteen | Gauteng |
| Tentacleman | |
| TEPSA (Pty) Ltd | Western Cape |
| Teraco Data Environments | Gauteng |
| Terra Digital | |