| Leading Edge Business Solutions | Gauteng |
| LeadRobot | Gauteng |
| Leggero Technologies | Gauteng |
| Legion Computer Accessories. | Gauteng |
| Lensil Technology | Gauteng |
| Let's Do It | Western Cape |
| Letaba TVET College | |
| Level 13 Communications | Gauteng |
| Level Finance | |
| LevelZero Communications | Western Cape |
| LexisNexis South Africa | Western Cape |
| Lexpro Systems Pty Ltd | Gauteng |
| LifeSADX (Pty) Ltd | |
| Limabean | Western Cape |
| Lime Green Digital (Pty) Ltd | |
| LimeHouse | Western Cape |
| Limenco Design | Gauteng |
| Limestone Residential Properties | Gauteng |
| Limtech | Gauteng |
| Linc | Western Cape |
| Linkable Analytics | |
| Linkfields Innovations (Pty) Ltd | |
| Linux Warehouse | Gauteng |
| Linuxweb | Gauteng |
| Liorra Tech (Pty) Ltd | |
| Lipa Payments | Western Cape |
| Liquid Thought | Western Cape |
| LIT Creations | Gauteng |
| Livemon | KwaZulu-Natal |
| Livesurf | Western Cape |
| Livex | |
| Logical Wireless | Gauteng |
| LogicSMS | Gauteng |
| Logitech SA | Gauteng |
| Logix Design and Development CC | KwaZulu-Natal |
| LooksGood Design Studio | KwaZulu-Natal |
| Lorge Consulting Services (Pty) Ltd | Gauteng |
| Lovedale TVET College | |
| Low Cost WebDesign | Free State |
| Ltech Dev | |
| Lucid Ocean | Western Cape |
| Luco Audio Electronics CC | KwaZulu-Natal |
| Luden Digital | |
| Lula Loop (Pty) Ltd | |
| Lulalend | |
| LVC Data Recovery | Gauteng |
| Lwazi Telecommunications CC | Gauteng |
| M&C Saatchi | Western Cape |
| MacWorks | Gauteng |
| Madberry Studio | Gauteng |