| Seez App-FZCO | Dubai |
| Selecto | |
| Sellanyphone.ae | Dubai |
| Sema Brands | |
| SemiDot Infotech | |
| Sensgreen | Abu Dhabi |
| SEO International Dubai | Dubai |
| SEO Out Of The Box | |
| SEO SOCIAL agency | |
| SEO SOUQ | Abu Dhabi |
| SEO Tech Experts | |
| SEO.ae | Dubai |
| SEOHUB UAE | |
| SEOSherpa | Dubai |
| Seven Media | Dubai |
| Shahid Maqbool | |
| Sharaf HQ Investment | Dubai |
| Sharjah Academy for Astronomy, Space Sciences and Technology | |
| Shazeb ICT | Abu Dhabi |
| Sheikh Studios | |
| Shipfinex | |
| Shoma.net | Dubai |
| Shorooq Partners | Abu Dhabi |
| SHUAA Capital | Dubai |
| Shuraa Advertising | |
| Si3 Digital | Dubai |
| SIGN4L | Abu Dhabi |
| Silicon Graphics | |
| Silicon Ways | Dubai |
| Silver Star Electronics, LLC | Dubai |
| Simage Technologies | Dubai |
| Simplex Himes | |
| Simplifai Labs | Dubai |
| SimpliFi | Dubai |
| Simtix FZ-LLC | Dubai |
| SISCA | |
| Sisgain | |
| Site Technology | Abu Dhabi |
| Sixty Seven Digital - FZCO | |
| Sketches Agency Dubai | |
| Skillphase | |
| Skit Solution BD | |
| SKY Electronics LLC | Dubai |
| Skycab | |
| SkyDelta | Dubai |
| Skyline University College | |
| Skytech Cyber Cloud | |
| Slicky Media | |
| Smaple IT Solutions | Dubai |
| Smart Call | Dubai |