| Epure S.A. | Fribourg |
| EquipE Solutions AG | Zurich |
| ErgoDent | Zurich |
| Ergon Informatik AG | Zurich |
| Ergonomics AG | Zurich |
| Ergosoft | Thurgau |
| ERNI Schweiz AG | Zurich |
| Ernst + Partner AG | Zurich |
| Ernst Basler + Partner AG | Zurich |
| Ersparniskasse Rüeggisberg Genossenschaft | |
| Ersparniskasse Schaffhausen | |
| Ersparniskasse Speicher | |
| ESA Business Incubation Centre Switzerland | |
| Escapenet.ch GmbH | Zurich |
| ESGroup AG | Zurich |
| EsoCap AG | |
| ETH Zürich - Department of Computer Science | |
| ETH Zürich - Department of Information Technology and Electrical Engineering | Zurich |
| ETH Zürich - Distributed Computing | Zurich |
| ETH Zürich - Distributed Systems Group | Zurich |
| ETH Zürich - Institute of Computer Systems | Zurich |
| ETH Zürich - Institute of Robotics | Zurich |
| ETH Zürich - Institute of Theoretical Computer Science | Zurich |
| ETH-Rat | Zurich |
| Ethereum | Zug |
| Ethereum Research | |
| Etrion Corporation | Geneva |
| Eulitha AG | |
| Euraconsult GmbH | Basel-Stadt |
| Euresearch | Bern |
| Eurisco S.à.r.l. | Ticino |
| Eurographics | Geneva |
| European Broadcasting Union | |
| European Graduate School | |
| EuroPython | Basel-Stadt |
| Eurospider Information Technology AG | Zurich |
| Eurovision Services | |
| Evalueserve AG | Schaffhausen |
| Evatec AG | |
| Eventor | |
| EverdreamSoft S.A. | |
| Evitria AG | |
| Evnnovatis Schweiz AG | Solothurn |
| Evoco AG | |
| Evok | Fribourg |
| Evolute AG | |
| EWM | |
| ExcellGene S.A. | |
| Execute GmbH | Zurich |
| Exeon Analytics AG | Zurich |