| Elanix Biotechnologies AG | |
| Elastiq GmbH | |
| Elatron AG | St. Gallen |
| ELCA Informatique S.A. | Vaud |
| Elcode AG | Thurgau |
| ELFI Formation S.à.r.l. | Geneva |
| Elinter AG | Zug |
| Elthera AG | |
| Elusiv | Zug |
| Elysion GmbH | Aargau |
| EM Microelectronic - Marin SA | Neuchâtel |
| Emakina.CH | Geneva |
| embotech AG | |
| EMC Electonics Media Communication S.A. | Ticino |
| Emerald Technology Ventures AG | Zurich |
| Emil Frey Digital AG | |
| Eminence | |
| Emonitor AG | |
| Emoticom AG | Bern |
| Emovo Care S.A. | |
| Empa | |
| Empira AG | |
| Empros GmbH | Thurgau |
| EMU Elektronik S.A. | Zug |
| Enairys Powertech | |
| Enantios | |
| Endeavour Vision Ltd | Geneva |
| Ender Informatics | Zug |
| Endeso GmbH | Zurich |
| Endurit Web Engineering GmbH | Zurich |
| Energy Startup Day | |
| Energy Web | |
| Engin Arslan | |
| Enkom AG | Lucerne |
| Enlightra | |
| Enloya | |
| Enso Finance | Zurich |
| Entec AG | Zurich |
| Enterprise Bot | Zug |
| Entex GmbH | Schwyz |
| Enzian Pharmaceutics Blaesi AG | |
| Enzyon | |
| EPFL - Institute of Mathematics | Vaud |
| EPFL Innovation Park | Vaud |
| EpiPharm AG | |
| Epiterna S.A. | |
| Epithelix | |
| EPS Software Engineering AG | St. Gallen |
| Epsitec S.A. | Vaud |
| Epteca GmbH | |