| Ujin | |
| UKR.Internet | Luhansk People's Republic |
| Umbrella IT | Moscow |
| Undef | Tatarstan |
| UNIM | |
| Unionsoft Plus LLC | Novosibirsk |
| Unipro UGENE | |
| UniSender | |
| Unisol-Apps.Com | |
| Unisound | |
| Unitile | |
| Unitsolutions | |
| Universal Math Solver | Saint Petersburg |
| Universe Ventures | Moscow |
| University of Artifial Intelligence | |
| University of Russian Innovative Education | |
| UPS-Shop.ru | Moscow |
| UR66.ru | Moscow |
| Ural Federal University | Sverdlovsk |
| Ural State University of Economics | Sverdlovsk |
| Urry Software Lab | Moscow |
| Usability в России | Moscow |
| Usabilitylab | Moscow |
| Usanov | Moscow |
| UserGate | Moscow |
| uWebDesign | |
| ValueHost | Moscow |
| vc.ru | |
| VCV.ru | Moscow |
| VDEL Ltd | Moscow |
| Ved-Soft | Moscow |
| VentaFax | Saint Petersburg |
| Ventra Go! | |
| Veon Ltd | Moscow |
| Vetsoft | Moscow |
| Vgshop | Moscow |
| Video2.biz | |
| ViewApp | Moscow |
| Viewizard | Luhansk People's Republic |
| Viju | |
| VimICQ | Tatarstan |
| VintaSoft Ltd | Rostov |
| Vinteo | |
| Vista Software | Moscow |
| Vita-soft | Moscow |
| VIVAstudio | |
| Vjoomla | Moscow |
| VK | Saint Petersburg |
| VK Cloud | |
| VK WorkSpace | |