| CoWorking 120 | Jalisco |
| CPM | Mexico City |
| Crabi | |
| Crabsys | Mexico City |
| Creadiseño, S.C. | Mexico City |
| CreandoWEBS | Jalisco |
| Creare | Puebla |
| Creasoft | Mexico City |
| CREATE Cowork AntiOficina | |
| Creative Software International | |
| CreativeSoft | |
| Creaxid | |
| Creditus | |
| Crehana | Mexico City |
| Creze | Mexico City |
| Cuadrangular | |
| Cuatromedios S.C. | Jalisco |
| Cubbo | |
| Cubicstone | Mexico City |
| Cuenca | Mexico City |
| Cutter Consortium América Latina | Mexico City |
| Cuuapps.mx | |
| CXC | |
| Cybac TI, S.A. de C.V. | Mexico City |
| Cyberideas, S.A. de C.V. | |
| CyberMaya | Mexico City |
| CyS-Software | Oaxaca |
| DA Soluciones IT | Mexico City |
| Dacompass | |
| DAD Software | Durango |
| Dalus Capital | Nuevo León |
| DAP Agency | |
| Dapp | Querétaro |
| Databilio | Mexico City |
| Dataproducts de México S.A. de C.V. | Mexico City |
| DataShield | Mexico City |
| DB Menos | Mexico City |
| Deduce Design | |
| DEK Automation de Puertas | State of Mexico |
| Delta Networks Systems | Mexico City |
| Denumeris | |
| Derevo | |
| Desarrollo 80 Diseño, S.C. | |
| Desarrollo de Sistemas Profesionales | Mexico City |
| Desarrollo de Sistemas Tiempo.Resultados | Quintana Roo |
| Desarrollo y Capacitación en Internet S. A. de C. V. | Mexico City |
| Desarrollos de TI, S.A. de C.V. | |
| Desarrollos Electrónicos y Eléctricos, S.A. de C.V. | Mexico City |
| Design Works | Nuevo León |
| DeSoftware, S.C. | |