| Igal Baum | |
| iguazio | Tel Aviv District |
| Iinformation Gates Ltd | Tel Aviv District |
| Illumigyn | Jerusalem District |
| iLog Accelerator | Tel Aviv District |
| iLogic | |
| ILPhotonics | Jerusalem District |
| Image-in | Central District |
| Imagecom Internet Technologies | Tel Aviv District |
| Imagu Vision Technologies Ltd | Tel Aviv District |
| Imark Image | |
| IMC Microwave Industries Ltd | Central District |
| iMDsoft | Tel Aviv District |
| IMK | Tel Aviv District |
| Immagnify | Central District |
| Immue | Tel Aviv District |
| Imoon | Northern District |
| ImPact Biotech | Central District |
| impact1st | Tel Aviv District |
| InboundJunction | |
| Incentive Management, Inc. | Judea and Samaria Area |
| Incentives Solutions Ltd | |
| Incubator for Technological Entrepreneurship Kiryat Weizmann Ltd | Central District |
| Incubit | Southern District |
| Inferno | Tel Aviv District |
| Infimé Development Ltd | Tel Aviv District |
| Infimé Development Ltd | |
| Infinity Labs R&D | |
| InfluencerMarketing.ai | Tel Aviv District |
| Infodraw Israel R&D Ltd | |
| Informat Computers Ltd | Tel Aviv District |
| Ingima Israel | |
| Inimiti Capital Partners | Tel Aviv District |
| Initech Software Services Ltd | Tel Aviv District |
| Initial Capital | Tel Aviv District |
| Inkod | Tel Aviv District |
| Inmanage | Tel Aviv District |
| Inmatrix | Haifa District |
| InNeGev | |
| InnoSec | Central District |
| Innovation Israel | Tel Aviv District |
| InnoviNet | Tel Aviv District |
| Innoviz Technologies Ltd | Central District |
| InnVentis Ltd | Central District |
| Inova Diamonds Ltd | |
| InovGate | Central District |
| Inpharmus | |
| Inpris Ltd | Jerusalem District |
| InsFocus Systems Ltd | Central District |
| Insightec Ltd | Haifa District |