| Spectrum Softtech Solutions Pvt Ltd | Kerala |
| Spectus Infotech | |
| Speech and Software Technologies (I) Pvt Ltd | Tamil Nadu |
| Speed Optimisation | Punjab |
| Speed Solutions | |
| Speedbox | Maharashtra |
| Speedcheck Pvt Ltd | Tamil Nadu |
| Speedweb Services, LLP | |
| Speedwell IT Solutions Pvt Ltd | |
| Spell Web InfoTech | Uttar Pradesh |
| Speqto Technologies Pvt Ltd | |
| Spera Digital Consulting Services Pvt Ltd | West Bengal |
| Speroware Technologies Pvt Ltd | Karnataka |
| SPG Technologies | |
| SPGON Software Solutions, LLP | |
| Sphaera Pharma Pvt Ltd | |
| Spheron | Karnataka |
| Sphinax Info Systems Ltd | |
| Sphinx Solutions Pvt Ltd | Maharashtra |
| Sphinx Worldbiz Ltd | Uttar Pradesh |
| Sphinx Worldbiz Ltd | |
| Sphoorthy Engineering College | |
| Spice Web Services | Tamil Nadu |
| SpiceGems | Rajasthan |
| Spicer Adventist University | |
| Spicetree Design Agency Pvt Ltd | Maharashtra |
| Spick Technologies | Gujarat |
| Spider Creations | Maharashtra |
| Spider India | |
| Spidergems | |
| SpiderOrbit Technologies | |
| SpiderWorks Technologies Pvt Ltd | |
| Spiegel Technologies | |
| Spiel Studios Pvt Ltd | Maharashtra |
| Spindigo Designs, LLP | |
| Spine Technologies | Maharashtra |
| Spinsage Technologies, LLP | |
| Spiral Mantra Pvt Ltd | |
| Spirangle Technologies | |
| Spire IT Services | |
| SpireHub Softwares Pvt Ltd | |
| Spirinova Technologies Pvt Ltd | Uttar Pradesh |
| SPJ Embedded Technologies Pvt Ltd | Maharashtra |
| Splendid Tech Systems Pvt Ltd | |
| Splitbit | |
| SPM IT Solutions | |
| Spoken Tutorial | Maharashtra |
| Spoors Technology Solutions India Pvt Ltd | Telangana |
| Spori Pvt Ltd | |
| SportsMechanics | Tamil Nadu |