| SouthField College, Darjeeling | West Bengal |
| Sova Infotech Pvt Ltd | |
| Sovarani Memorial College | |
| Sovereign Software Solutions | |
| SP Infocom | |
| SP Jain Institute of Management | Maharashtra |
| SP Software (P) Ltd | Telangana |
| SPAARG InfoSolutions | |
| Space Applications Centre | |
| Space Cloud | Maharashtra |
| Space Office Systems (I) Pvt Ltd | Maharashtra |
| Space Stem | |
| Space Tem | |
| Space-O Technologies | |
| Space2host | Tamil Nadu |
| Spacebar | |
| Spacecos Solutions Pvt Ltd | Maharashtra |
| SpaceFields Pvt Ltd | |
| SpaceNet Enterprises India Ltd | Telangana |
| Spaculus Software Pvt Ltd | Gujarat |
| Spaising Technology | |
| SparcByte | |
| Spark Eighteen Lifestyle Pvt Ltd | |
| Spark Innovations Pvt Ltd | |
| Spark Studios | Tamil Nadu |
| Spark Technologies | |
| SparkBrains | |
| Sparkout Tech | |
| SparkSupport Infotech Pvt Ltd | Kerala |
| Sparkup Technology Pvt Ltd | |
| SparrowGenie | |
| Sparsh Communications Pvt Ltd | Telangana |
| Sparsh Technologies | |
| Sparsh Technologies Pvt Ltd | |
| Sparshik Technologies Pvt Ltd | |
| SpartanLabs | |
| Sparx | Uttar Pradesh |
| Sparx Technologies Pvt Ltd | Jharkhand |
| Spawn Point | Madhya Pradesh |
| Spawoz | Kerala |
| Spearmint | |
| Spec India | Gujarat |
| Specbee Consulting Services Pvt Ltd | |
| Specgraph (India) Pvt Ltd | Maharashtra |
| Speciale Invest | Tamil Nadu |
| Spectranet | Haryana |
| Spectrics Solutions Pvt Ltd | |
| Spectrum Computer & Management Consultancy (SCMC) Pvt Ltd | Maharashtra |
| Spectrum Exploring Technology | |
| Spectrum Infotech Pvt Ltd | West Bengal |