| Ryax Technologies | |
| Rzilient | |
| S & H Group | Paris |
| S-Designer.com | Hérault |
| S4E - Energysoft | |
| Saagie | |
| Saaswedo | |
| SAB International | Hérault |
| Sacasa | Eure-et-Loir |
| Sacha LB | |
| Safari des métiers du numériques | Loire-Atlantique |
| SAFE | |
| SafeBrands | Paris |
| SafeHeal, Inc. | |
| Safeo | Hauts-de-Seine |
| Safran | |
| Saft | |
| Saft Groupe S.A.S. | |
| SAFTI | |
| Sagemcom Broadband S.A.S. | Hauts-de-Seine |
| Sagimeca | |
| SAILING communication & technologies | Val-de-Marne |
| Saint-Gobain | |
| SAITEC S.A.R.L. | Saône-et-Loire |
| Salemioche S.A.R.L. | Alpes-Maritimes |
| Salesapps | |
| SalesMind Ai | |
| Salezero | Hauts-de-Seine |
| Salies | Essonne |
| Salon international de l'aéronautique et de l'espace | |
| Sam-Mag.com | Gironde |
| Samabriva | |
| Sami.eco | |
| SAMSYS | |
| Sand to Green | |
| Sangha | Bouches-du-Rhône |
| Sanilea | |
| Sanofi | |
| Santiane | |
| Saphelec | Alpes-Maritimes |
| Saphir Consult | Paris |
| Saqara | |
| Sarbacane Software | Nord |
| Sariel | Paris |
| Sarus Technologies | |
| Satavenue | Val-d'Oise |
| Satel | |
| Satelia | |
| SATT Conectus | |
| Satt Lutech | |