| StudioKraft Creative Web Services, LLC | New Jersey |
| StudioLine | New Jersey |
| StudioPlus Software, LLC | Florida |
| Studioschoolpro | Massachusetts |
| Study Abroad 101, LLC | |
| StudyLamp Software | Oklahoma |
| Studylog Systems, Inc. | California |
| Studypool, Inc. | |
| Stuff Software, Inc. | Florida |
| Stumari, LLC | |
| Stun Design & Interactive | |
| Stunning | Louisiana |
| Stunt&Gimmick's, LLC | |
| Stunz Konstantin | Florida |
| Sturdy | Oregon |
| Sturges Electronics Co., Inc. | New York |
| Sturppy | Colorado |
| Stuzo | Pennsylvania |
| Styku | California |
| Style Advertising | |
| StyleAI | California |
| Stylefish, Inc. | Minnesota |
| StyleSage | California |
| StyleScan | California |
| Styliff, Inc. | |
| Stylitics | |
| Stylus Medicine, Inc. | Massachusetts |
| Stylus Studio | Massachusetts |
| Styra | California |
| Stytch | California |
| Styx Biotechnologies | California |
| Sub Systems, Inc. | Texas |
| SubBase | |
| SubioMed, Inc. | Minnesota |
| SubIT | Florida |
| SubitUp, Inc. | New Hampshire |
| Subject | |
| SubjectWell | |
| Sublime Creative Agency | |
| Sublime Global | |
| Sublime Media | Washington |
| Sublime Security, Inc. | |
| Sublime Systems | |
| Subliminal Pixels Lab Co. | Florida |
| Sublunar Networks | California |
| SubMain Software | Washington |
| Submig, LLC | |
| Submit AI Tools | |
| Submit Express | California |
| SubmitNet, Inc. | Idaho |