| Strivr | California |
| Strivve | Washington |
| Strix Technology Group | |
| STRM.BIO, Inc. | Massachusetts |
| Strobe Data, Inc. | Washington |
| Strobes Security, Inc. | Texas |
| StrokeDx | California |
| StrÅma Medical Corporation | |
| Stromasys, Inc. | North Carolina |
| Stromberg Sport, LLC | |
| Strong Analytics | |
| Strong Controls | Louisiana |
| Strong Crypto Innovations, LLC | Virginia |
| Strong Design Studios, LLC | |
| Strong Tower Consulting | Washington |
| Strong Ventures, LLC | California |
| Strongarm | |
| strongDM | California |
| StrongestLayer | |
| Stronghold Cyber Security, LLC | Pennsylvania |
| Stronghold Data | Missouri |
| StrongLoop | California |
| StrongMind | Arizona |
| StrongSuit AI, Inc. | |
| Strottner Designs, LLC | Texas |
| Strowger, Inc. | Missouri |
| StrtupBoost | New York |
| Structure Capital | California |
| Structure Fund | |
| Structure Medical | Florida |
| Structure Studios | Nevada |
| Structure Therapeutics, Inc. | |
| Structure X | Louisiana |
| Structured Cable Products, Inc. | Florida |
| Structured Domains | Texas |
| Structured Technology | Kentucky |
| Structured, Inc. | Oregon |
| StructuredWeb, Inc. | New York |
| StructurePoint, LLC | Illinois |
| Strumly | California |
| Strunk, LLC | |
| Struoweb | |
| StruxHub | |
| STRV | California |
| Stryde | Utah |
| StrykaGen Corporation | |
| Stryper Technologies | Minnesota |
| STS Consulting | New Jersey |
| STS Instruments, Inc. | California |
| STS Software | |