| Keifi Technologies | Madrid |
| Keiretsu Forum Spain | Barcelona |
| Keld | Zaragoza |
| Kenmei Technologies | Valencia |
| Kepar | Zaragoza |
| Kerionics | Valencia |
| Kern Pharma | |
| KeyZell | Sevilla |
| Kibo Ventures | Madrid |
| Kierke Desarrollo Web, S.L. | Barcelona |
| Kiin | |
| Kimaldi | Barcelona |
| Kimia Solutions, S.L. | Madrid |
| Kimitec Biogroup, S.L. | |
| Kineox Solutions, S.L. | Madrid |
| King of App | Lleida |
| KingEclient | Barcelona |
| Kingseo Eats the World, S.L. | |
| Kintai | Barcelona |
| Kirab | Barcelona |
| klicap - ingeniería del puzle, S.L. | Sevilla |
| Klik & Spik | Madrid |
| Kloov | Barcelona |
| KMA Disseny & Marketing, S.L. | |
| knowCentury | Madrid |
| Knüt Studio | |
| Koa Health | Barcelona |
| Komunika Digital | Álava |
| Konecta Group | Madrid |
| Konfigear | |
| Kontrol Web | Valencia |
| Koonstel | Barcelona |
| KOR multimedia | Burgos |
| Korku Soft | A Coruña |
| Korra Studio | Biscay |
| Kraken Informática | Valencia |
| KrakenD, S.L. | |
| Krama e-soft, S.A. | Madrid |
| Krasis.com | Pontevedra |
| Kreanto Services | Castellón |
| Kreios Space | |
| Kriter Software | Barcelona |
| KRSolutions | Madrid |
| Kubide | |
| Kymatio | Madrid |
| Kymos Group | Barcelona |
| L'Agence CDRS | Málaga |
| L.A.B. CIRCUITS, S.A. | Barcelona |
| L.A.S.E.R., S.L. | Santa Cruz de Tenerife |
| La Biznaga Digital | |