| Devengo, S.L. | Madrid |
| Devialab, S.L. | Madrid |
| DevilishGames | Alicante |
| Devlon | Biscay |
| Devoluiva | Barcelona |
| Devops Barcelona Conference | Barcelona |
| Devservice | |
| DEXMA Sensors, S.L. | Barcelona |
| Dexva | Madrid |
| Deyde Datacentric, S.L.U. | Madrid |
| Dezzai | Madrid |
| DFactory Barcelona | Barcelona |
| Dfutura Soluciones Multimedia, S.L. | Madrid |
| Dhap Center, S.L. | Valencia |
| DHV Technology | |
| Diálogo Tecnológico | Ciudad Real |
| Dicoel, S.L. | Barcelona |
| Dicop Consulting | Madrid |
| Digepro Informatica Profesional | Zaragoza |
| Digi Procés | Barcelona |
| DIGI Spain Telecom, S.L.U. | Madrid |
| Digibit | Madrid |
| Digital Addiction | Madrid |
| Digital Astures | Asturias |
| Digital Avenue | Barcelona |
| Digital Domain, S.L. | Madrid |
| Digital Finance | Madrid |
| Digital Futura | Madrid |
| Digital Group Branch, S.L. | Madrid |
| Digital Growth | Barcelona |
| Digital Legends Entertainment, S.L. | Barcelona |
| Digital Málaga | Málaga |
| Digital Nature | Alicante |
| Digital Samba, S.L. | Barcelona |
| Digital XXL | Madrid |
| DIGITAL55 | Madrid |
| DigitalCreativos | Murcia |
| digitalDot | |
| Digitalis | Murcia |
| Digitec C2 cloud | Gipuzkoa |
| Digitmedia | |
| Digitup Studio, S.L. | Madrid |
| DIH·Bio | Madrid |
| DilyaSoft | |
| Dimensiona Consultoría Tecnolóxica | A Coruña |
| Dimo Visual Creatives, S.L. | Barcelona |
| Dimosa | Madrid |
| Dinacell Electrónica, S.L. | Madrid |
| Dinahosting | A Coruña |
| Dinamicsweb | Barcelona |