| Telindus | Luxembourg |
| Telkea ICT S.A. | Luxembourg |
| TenTwentyFour S.à.r.l. | Capellen |
| Tetrao | |
| Tetris Communication | |
| The IT Department.net | Luxembourg |
| The Lordz Games Studio | Luxembourg |
| The Network | |
| The Office Luxembourg | |
| The Recruiter S.à r.l. | |
| TheMarketsTrust | Luxembourg |
| ThreeFold S.A. | |
| TMRW Foundation S.à r.l. | |
| Tokeny S.à r.l. | |
| Tokeny Solutions | Esch-sur-Alzette |
| Tolerogenics S.à r.l. | |
| Tomorrow Street | Luxembourg |
| Traffic Club S.A.R.L. | Luxembourg |
| TransArdenna S.A. | Luxembourg |
| Travelsify S.A. | Luxembourg |
| Traxxion S.A. | |
| TreeTop | |
| Tuomi S.A. | |
| Ujet International S.à r.l. | |
| Ume | |
| Unigine | Luxembourg |
| Université du Luxembourg - SnT, Interdisciplinary Centre for Security, Reliability and Trust | Luxembourg |
| University of Luxembourg | Esch-sur-Alzette |
| University of Luxembourg - Department of Mathematics | Esch-sur-Alzette |
| University of Luxembourg - Faculty of Science, Technology and Medicine | Esch-sur-Alzette |
| University of Luxembourg - Interdisciplinary Centre for Security, Reliability and Trust | Esch-sur-Alzette |
| University of Luxembourg - Luxembourg Centre for Systems Biomedicine | Esch-sur-Alzette |
| Uplift360 | |
| Urban Office | |
| UX Capital | |
| Value4Capital S.à r.l. | |
| Vanksen | Luxembourg |
| Velcan Holdings | |
| Vesalius Biocapital Partners S.à r.l. | |
| Viber Media S.à r.l. | Luxembourg |
| VIRELUX Inspection Systems S.à r.l. | |
| Visual Online S.A. | Luxembourg |
| voipGATE S.A. | Luxembourg |
| Vox Capital | |
| Warden Machinery S.à r.l. | |
| web-design.lu | |
| WebPros | |
| Women Cyber Force | |
| Women in Business, A.s.b.l. | |
| Women in Digital Empowerment | Luxembourg |