| Service Hard | Buenos Aires |
| Servicios Internet | Buenos Aires |
| Servicios y Sistemas de Computación | Buenos Aires |
| SES Sistemas Electrónicos S.A. | Buenos Aires |
| Seta Sistemas | Buenos Aires |
| SextaGeneración | Buenos Aires |
| SIADNet | Buenos Aires |
| SIASA | Buenos Aires |
| Siblings Software | |
| Sidesys IT Solutions | Buenos Aires |
| Sierra Technology Group, S.A. | Buenos Aires |
| Siglo Informática | Buenos Aires |
| Signos | Buenos Aires |
| SimplesPasos.com | Buenos Aires |
| SimplificarWeb | Buenos Aires |
| SimulAr | Buenos Aires |
| Simza Computacion | Buenos Aires |
| Siscard S.A. | Córdoba |
| Siscard S.A.. | Buenos Aires |
| Sisgra | Santa Fe |
| Sisted | Buenos Aires |
| Sistek | Buenos Aires |
| Sistema de Informes Laborales | Buenos Aires |
| Sistema Isis | Buenos Aires |
| Sistemas Aplica | Buenos Aires |
| Sistemas Criticos | Buenos Aires |
| Sitios Hispanos | Santa Fe |
| siwol.com.ar | Buenos Aires |
| Skyonline | Buenos Aires |
| Skytel | Buenos Aires |
| Smallcode | Buenos Aires |
| smartGSM | Buenos Aires |
| SmartSol | Buenos Aires |
| Snappler | Buenos Aires |
| Snoop Consulting | Buenos Aires |
| SocialTools.me | Buenos Aires |
| Sociedad Argentina de Informacion | Buenos Aires |
| Sociedad Argentina de Informática | Buenos Aires |
| Sociedad Científica Argentina | Buenos Aires |
| Sofiana | Buenos Aires |
| Sofrecom Argentina | Buenos Aires |
| Softland Argentina | Buenos Aires |
| Software América | Buenos Aires |
| Software del Centro | Buenos Aires |
| Software Legal | Buenos Aires |
| SolSoft S.R.L. | Buenos Aires |
| Solsoftware | Buenos Aires |
| Soluciones Nexo S.A. | Córdoba |
| Solutica Software Development Company | Buenos Aires |
| Sonda | Buenos Aires |