| Critical | Vilnius |
| Cyber Upgrade | |
| Cybergizer, LLC | |
| Dagvita | Kaunas |
| Data Miner Ltd | |
| DataEngi | |
| DATALOGIC commerce | |
| DealLink | |
| Debetas UAB | Vilnius |
| DeepFin | |
| Delta Biosciences | Vilnius |
| Dental4Windows | Vilnius |
| Dev2dev Ltd | |
| DevDays | |
| Devima Solutions | Vilnius |
| DevOps Pro Europe | |
| digetiers Spice | |
| Digital Matter | |
| Digital Partners | |
| Digital Sense | |
| Digital Sense | |
| DigitalStar | |
| Digitouch, UAB | |
| DIMEX technologies | Vilnius |
| DocLogix | |
| DoctorPC | Vilnius |
| Domains.lt | Kaunas |
| Domreg.it | Kaunas |
| Dragon.lt | Vilnius |
| Droplet Genomics | Vilnius |
| Dserve | |
| E-Bros | |
| E-Cloud | |
| E-Guider | |
| e-saugumas | Vilnius |
| EasyFlow | |
| EasySEO | Vilnius |
| EASYSEO.LT | |
| EasyWeb | Vilnius |
| ECM Studija, UAB | |
| eComCharge, UAB | |
| Edata | |
| Eddy AI | |
| Eddy Travels | |
| eddy.lt | Vilnius |
| Edfluence | |
| EditAI | |
| Edrana Baltic | Vilnius |
| Edu Challenger | |
| Ekonomikos ir kaimo vystymo institutas | |