| Digisound.ee | Harju |
| Digistep OÜ | Pärnu |
| Digital Fruit | Harju |
| Digital Invest OÜ | |
| Digital Magic OÜ | |
| Digital Sputnik Lighting | |
| DigitalMara | |
| Digitugi | |
| Digiturundus | |
| DIgu | Tartu |
| Diotech OÜ | |
| Divectors | |
| doCode Development OÜ | |
| Dolm IT | |
| DreamApply | |
| DriveX Technologies OÜ | |
| DriveX Technologies OÜ | |
| DRL OÜ | Harju |
| Dron.ee | |
| Drops | |
| DrugCard OÜ | |
| Duplicator 24/7 | Harju |
| Dysnix | |
| e-Estonia | Harju |
| e-Government Academy | |
| E-Kursused | Harju |
| E-People OÜ | Harju |
| E-pood OX Eesti OÜ | Harju |
| e5.ee | |
| eAgronom OÜ | |
| EastBAN | |
| EchoGlobal OÜ | |
| Ecofleet Eesti OÜ | Harju |
| eD Insenerid | |
| Edicy | Harju |
| Edisoft | Harju |
| Edulegal | |
| Edunet OÜ | Harju |
| EENet | Tartu |
| Eesti Infotehnoloogia Kolledž | Harju |
| Eesti Interneti Sihtasutus | Harju |
| Eesti Keele Instituut | |
| Eesti Koolitehnika | |
| Eesti Maaülikool | |
| Eesti Pank | |
| Eetasoft | Harju |
| EFCC Estonian Fieldbus Competency Centre OÜ | Harju |
| Efenco | |
| eHouse CA | Harju |
| EJAW | Harju |