| Marcel A. Hug Informatik GmbH | Zurich |
| MarcSimum Support | Aargau |
| Marine Electronic S.à.r.l. | Vaud |
| Marketing With Singh | |
| Martha Software GmbH | Aargau |
| Marti IT Services | Solothurn |
| Martin Grandjean | |
| Martin Weiss Informatik AG | Zug |
| Martinig & Associates | Vaud |
| Marvelous Digital S.A. | |
| Master 21 | |
| Masterhomepage GmbH | Basel-Stadt |
| Mastertools GmbH | Aargau |
| MathConsult Ltd | Schwyz |
| Mathias Hartmann Werbung | Zurich |
| Mathias Payer | |
| Mathys AG Bettlach | |
| Matronic S.A. | Valais |
| MAW Software Ltd | Schwyz |
| Maximon | |
| MaxiVAX | |
| Mayoris AG | Zug |
| Mazero | Geneva |
| Mazursoft GmbH | Lucerne |
| mCHinformatique | Neuchâtel |
| MCS Software AG | Bern |
| MDF-BIS S.A. | Vaud |
| Measys | Solothurn |
| Mechmine, LLC | |
| Medacta International | |
| Medartis AG | |
| media.art | Zurich |
| Mediadiscount.ch | Aargau |
| Mediagraphix | Zurich |
| MediaGroup Worldwide AG | Zug |
| Medigene AG | |
| Medio-Ingeno AG | Zurich |
| Medmix | |
| Meerstetter Engineering GmbH | Bern |
| Megacad-Center GmbH | Zurich |
| Mégamail | Vaud |
| Megaphone | |
| Mégaphone Internet | Vaud |
| mehlau.net | Zurich |
| Melde - und Analysestelle Informationssicherung MELANI | Bern |
| Melodia Therapeutics | |
| Memo Therapeutics AG | |
| Mémoire Vive | Vaud |
| Menea Menzi Engineering AG | Glarus |
| Mepha Schweiz AG | |