| Spher | |
| Sphinxly AB | |
| Spiffbet | |
| Spiideo | |
| Spinit AB | Västra Götaland |
| Spintop Ventures | |
| Spiro Kommunikation | Västra Götaland |
| Splitter.ai | |
| SPM Instrument AB | |
| Spoke Digital Agency AB | Stockholm |
| Sport Competence Sweden AB | |
| SportAdmin | |
| Sportality | |
| Sportswik AB | Västerbotten |
| Spotify AB | |
| Spotin AB | |
| Spotscale | |
| Springflod AB | |
| Springville Scandinavia AB | |
| Sprint Bioscience | |
| Sprintcrowd AB | |
| Spritju | |
| SP_CE Technologies | |
| Sqb Webbyrå AB | |
| SQORD | |
| SQUID App, Njuice AB | |
| Stabelo AB | |
| Standout Capital | |
| Star Stable Entertainment AB | |
| Star Vault AB | Skåne |
| Starbreeze Studios | Stockholm |
| Starcounter AB | Stockholm |
| Stardots AB | |
| StarFlow AB | Stockholm |
| Starhive AB | |
| Starmony AB | |
| Starq Agency | Skåne |
| Start Communication | |
| Startup Sthlm | |
| Startup Studio | Skåne |
| Startup Sweden | Stockholm |
| Startupgrind.se | |
| StartupTools Europe AB | |
| Starweb | |
| Stateless Digital | |
| Stayble Therapeutics | |
| Staylive AB | |
| Steamcore | |
| Steep Analytics | |
| Stegra | |